2,5-Dichloroaniline CAS 95-82-9
2,5-Dichloroaniline CAS 95-82-9 2,5-Dichloroaniline was used in a study to develop a fast and sensitive quantitative method for the detection
2-Amino-5-chlorobenzotrifluoride CAS 445-03-4
2-Amino-5-chlorobenzotrifluoride is an aromatic amine intermediate containing chlorine and trifluoromethyl substituents, widely used in the synthesis of pharmaceuticals and agrochemicals.
2-Amino-5-chlorobenzotrifluoride CAS 445-03-4
- CAS: 445-03-4
- Molecular Formula: C7H5ClF3N
- Molecular Weight: 195.57
- EINECS: 207-151-3
- HS Code: 29214300
- Synonyms: 2-Amino-5-chlorobenzotrifluoride 97%; 2-Amino-5-chlorobenzotrifluoride97%; 4-Chlor-alpha,alpha,alpha-trifluor-o-toluidin; 2-Amino-5-chlorobenzotrifluoride, 4-Chloro-α,α,α-trifluoro-o-toluidine; Benzenamine, 2-trifluoromethyl-4-chloro; Diazo Fast Scarlet VDA; Fast Scarlet Base VD; FA-1-1
What is 2-Amino-5-chlorobenzotrifluoride CAS 445-03-4?
2-Amino-5-chlorobenzotrifluoride CAS 445-03-4 is a halogenated aromatic compound featuring both amino and trifluoromethyl groups, which impart high chemical reactivity and stability. It serves as an essential building block in the manufacture of complex organic molecules, particularly in the pharmaceutical and pesticide industries, due to its versatile functional groups and electron-withdrawing effects.
Specifications
| Property | Value |
|---|---|
| Melting Point | 8.8 °C |
| Boiling point | 66-67 °C3 mm Hg(lit.) |
| Density | 1.386 g/mL at 25 °C(lit.) |
| Color | Colorless to Orange to Green |
| Form | clear liquid |
| Fp | 203 °F |
| pka | 0.83±0.10(Predicted) |
| Ph | 7.4 at 20℃ and 995mg/L |
| Storage Temp. | 2-8°C |
Features
- Contains reactive amino and electron-withdrawing CF₃ and Cl groups for versatile chemical modification.
- High thermal and chemical stability.
- Useful intermediate for introducing fluorinated and chlorinated moieties into target molecules.
- Offers enhanced lipophilicity and metabolic stability to derived compounds.
Applications
- Pharmaceuticals: Intermediate in the synthesis of active pharmaceutical ingredients (APIs) such as fluoroquinolone antibiotics and other aromatic amines.
- Agrochemicals: Used in producing herbicides, fungicides, and insecticides.
- Dyes and Pigments: Precursor for specialty dyes and colorants.
- Chemical Research: Applied in the development of fluorinated organic compounds and fine chemicals.
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