3-Chlorophenyl Isocyanate CAS 2909-38-8

What is 3-Chlorophenyl Isocyanate CAS 2909-38-8?

3-Chlorophenyl Isocyanate CAS 2909-38-8 is a highly reactive aromatic isocyanate intermediate, featuring a reactive -NCO group and a chloro-substituted benzene ring. It is moisture-sensitive, lachrymatory, and widely used in the synthesis of urea derivatives, carbamates, pharmaceuticals, agrochemicals, and polyurethane modifiers.

Specification

Feature

• Highly Reactive -NCO Group: Rapidly reacts with amines, alcohols, and thiols to form ureas, carbamates, and thiocarbamates.
• Moisture Sensitive: Decomposes in contact with water, releasing CO₂ and corresponding aromatic amine.
• Good Solubility: Soluble in most anhydrous organic solvents (toluene, dichloromethane, ethyl acetate).
• Stable Under Inert Conditions: Remains stable when stored properly under dry nitrogen or argon.
• Strong Lachrymator: Requires strict protective equipment and sealed operating conditions.

Application

• Pharmaceutical Intermediates: Key building block for sulfonylurea drugs, sedatives, and other APIs.
• Agrochemicals: Intermediate for herbicides, insecticides, and urea-based plant growth regulators.
• Fine Chemicals: Synthesis of substituted ureas, carbamates, and heterocyclic compounds.
• Polyurethane Modification: Used as a chain extender, crosslinker, and blocking agent for PU systems.
• Organic Synthesis Reagent: Protective agent and derivatization reagent for amines in research.

Packaging

Mikem offers secure packaging for moisture-sensitive hazardous liquids, including sealed steel drums and ISO tanks, all customizable under strict inert and dry conditions.