5-chloro-2-(4-chlorophenoxy)-benzenamin CAS 121-27-7

5-Chloro-2-(4-chlorophenoxy)benzenamine (CAS 121-27-7) is a halogenated aromatic amine compound serving as a versatile building block in organic synthesis, particularly for dyes and pharmaceutical intermediates due to its reactive amino group and ether linkage.
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5-chloro-2-(4-chlorophenoxy)-benzenamin CAS 121-27-7

What is 5-chloro-2-(4-chlorophenoxy)-benzenamin CAS 121-27-7?

5-chloro-2-(4-chlorophenoxy)benzenamine CAS 121-27-7 is a chlorinated aromatic amine with an ether-linked structure (C₁₂H₉Cl₂NO, 254.11 g/mol), combining reactivity (amino/chlorine groups) for nucleophilic reactions. It enables vibrant textile dyes, potential therapeutics, and proteomics research. Synthesized via nitro-reduction or etherification, it bridges lab chemistry to industrial and biomedical innovations.

Specifications

Property Value
Melting point 61.0 to 65.0 °C
Boiling point 234°C/27mmHg(lit.)
Density 1.386 g/mL at 25 °C(lit.)
Color White to Yellow to Orange
Form powder to crystal
pka 2.99±0.10(Predicted)
Storage Temp. Keep in a dark place, Inert atmosphere, Room temperature

Features

  • Physical Properties: Solid at room temperature with a melting point of ~67°C; soluble in organic solvents like ethanol or acetone, but limited water solubility due to its non-polar aromatic structure.
  • Chemical Reactivity: The primary amino group enables nucleophilic reactions, such as diazotization or coupling, while the ether linkage provides stability; the chlorine substituents enhance lipophilicity and metabolic resistance in derived compounds.
  • Safety Profile: Harmful if swallowed, inhaled, or absorbed through skin; causes eye and skin irritation; handle with protective equipment in well-ventilated areas, as it may release toxic fumes when heated.

Applications

  • Dye Synthesis: Acts as an intermediate for azo and acid dyes, including high-fastness disperse dyes, due to its ability to form colored complexes in textile coloration.
  • Pharmaceutical Intermediates: Used in the preparation of bioactive molecules, such as potential antifungal or anti-inflammatory agents, leveraging its halogenated structure for drug-like properties.
  • Research and Biochemical Tools: Employed in proteomics and organic synthesis for creating enzyme inhibitors or fluorescent probes, often in academic and industrial R&D.

Packaging

Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.

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