What is Tetrabutylammonium Fluoride CAS 429-41-4?
Tetrabutylammonium fluoride CAS 429-41-4 is an organic-soluble fluoride salt that provides a convenient source of free fluoride anions in non-aqueous systems. It is widely used as a base, phase-transfer catalyst, and fluorinating reagent in synthetic chemistry. The fluoride ion in this compound behaves as a relatively “free” nucleophile, enabling efficient reactions in organic media.
Specifications
| Property |
Value |
| Appearance |
Clear light greenish to brown solution |
| Melting Point |
62–63 °C |
| Density |
0.953 g/mL at 25 °C |
| Storage conditions |
Store at 2–8 °C |
Features
- Highly Reactive Fluoride Source: Provides accessible fluoride ions with strong nucleophilicity for demanding organic transformations.
- Excellent Organic Solubility: Readily miscible with common polar organic solvents, supporting homogeneous reaction systems.
- Multi-Functional Reagent: Functions as a base, phase-transfer catalyst, and fluorination reagent in synthetic workflows.
- Moisture Sensitive: Hygroscopic nature requires controlled handling and dry storage conditions.
Applications
- Deprotection Chemistry: Widely used for cleavage of silyl protecting groups in organic synthesis.
- Nucleophilic Fluorination: Serves as a convenient fluoride donor in preparation of fluorinated organic compounds.
- Phase-Transfer Catalysis: Applied to enhance reactions involving ionic species in organic media.
- Fluoride Sensor Research: Used as a measurable fluoride anion source in analytical and sensing studies.
Packaging
Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.
