Nimbolide CAS 25990-37-8

What is Nimbolide CAS 25990-37-8?

Nimbolide CAS 25990-37-8 is a naturally occurring limonoid (triterpenoid) compound isolated from the neem tree (Azadirachta indica), particularly from its leaves, flowers, and edible parts. It is widely studied for its biological and pharmacological activities, especially its anticancer potential, as it has been shown to inhibit the growth of various human cancer cell lines by inducing apoptosis, cell cycle arrest, and modulation of multiple signaling pathways. Nimbolide is commonly used as a research compound in pharmaceutical and biomedical studies related to anticancer, anti-inflammatory, and antioxidant mechanisms.

Specification

Feature

• Natural triterpenoid: isolated from the edible parts of the neem tree (Azadirachta indica).
• Anticancer activity: exhibits moderate to very strong growth-inhibitory activity against human colon carcinoma HT-29 cells in vitro.
• Dose-dependent activity: shows biological activity within the micromolar range (2.5–10 μM), suitable for pharmacological and mechanistic studies.

Application

• Anticancer research compound: showing significant growth-inhibitory activity against human colon carcinoma HT-29 cells.
• Cell biology & oncology studies: to investigate dose-dependent antiproliferative effects (2.5–10 μM).
• Natural product & drug discovery: focusing on bioactive triterpenoids from Azadirachta indica (neem tree).

Packaging

Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.