Hydroxypropyl-beta-cyclodextrin CAS 94035-02-6

What is Hydroxypropyl-beta-cyclodextrin CAS 94035-02-6?

Hydroxypropyl-beta-cyclodextrin CAS 94035-02-6 is a hydroxyalkylated derivative of β-cyclodextrin produced by reacting β-cyclodextrin with propylene oxide. This modification significantly enhances its aqueous solubility compared to native cyclodextrin, enabling it to form stable inclusion complexes with hydrophobic molecules. It is widely used in pharmaceutical, food, and cosmetic industries as a functional excipient to improve drug delivery performance, stabilize active ingredients, and enhance formulation efficiency.

Specifications

Features

• Outstanding Solubilization Ability: Forms inclusion complexes with poorly soluble compounds, significantly enhancing aqueous solubility and dissolution performance.
• Enhanced Bioavailability: Improves drug absorption and therapeutic efficiency by increasing solubility and stability of active ingredients.
• High Water Solubility vs β-CD: Compared with native β-cyclodextrin, HP-β-CD exhibits much higher solubility, enabling broader formulation applications.
• Excellent Safety & Biocompatibility: Demonstrates low toxicity and good tolerance, suitable for oral, injectable, and topical formulations.

Applications

• Pharmaceutical Formulations: Widely used as a solubilizer and stabilizer in oral liquids, tablets, injections, inhalation, and topical formulations.
• Drug Delivery Systems: Applied to improve bioavailability, control drug release, reduce toxicity, and enhance stability of APIs.
• Food & Beverage Industry: Used to improve flavor stability, mask odors, and enhance emulsification and moisture retention properties.
• Cosmetics & Personal Care: Functions as a stabilizer, encapsulating agent, and active ingredient carrier in skincare and cosmetic formulations.

Packaging

Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.