Rizatriptan CAS 144034-80-0

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Rizatriptan CAS 144034-80-0

CAS: 144034-80-0
Molecular Formula: C15H19N5
Molecular Weight: 269.34
EINECS: /

Synonyms: CS-281; Rizatriptan; Rizatriptan-d3; 2-(5-((1H-1,2,4-Triazol-1-yl)methyl)-1H-indol-3-yl)-N,N-dimethylethanamine; N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine

What is Rizatriptan CAS 144034-80-0?

Rizatriptan CAS 144034-80-0 is a triptan class indole derivative that functions as a selective agonist of serotonin 5-HT1B and 5-HT1D receptors, making it relevant in studies of vasoconstriction and neurochemical pathways associated with acute migraine relief and cranial blood vessel modulation. It is supplied as a white to off-white crystalline solid and is used as a reference compound or intermediate in neuropharmacology and medicinal chemistry research.

Specification

Item Value
Appearance White to off-white crystalline solid
Melting Point 178–180 °C
Boiling Point ~504.8 °C (predicted)
Density ~1.21 g/cm³ (predicted)
Storage Condition Store under inert gas at 2–8 °C, cool and dry place

Feature

  • Selective Serotonin Receptor Agonist– Functions as a 5-HT1B/1D receptor agonist, making it a key molecule in studies of serotonergic signaling and vasoconstrictive mechanisms relevant to migraines.
  • Defined Crystalline Solid– Exhibits a clear melting point and stable solid form, facilitating handling, purification, and analytical characterization in laboratory settings.
  • Neuropharmacological Research Utility – Used as a reference standard or intermediate in medicinal chemistry and neurobiological investigations into headache treatments and serotonin-mediated pathways.

Application

  • Neuropharmacology Research– Applied in studies of serotonin receptor interactions, vasoconstriction and neuronal signaling pathways.
  • Migraine Mechanism Investigation– Used as a research compound in experiments related to acute migraine and cranial blood vessel modulation.
  • Medicinal Chemistry & Analytical Studies– Serves as a reference standard or intermediate for drug design, synthetic modifications, and analytical method development.

Packaging

Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.

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