3-Chloro-2-methylaniline CAS 87-60-5
3-Chloro-2-methylaniline is an aromatic amine compound used as an intermediate in the synthesis of dyes, pharmaceuticals, and agrochemicals. Home /
5-chloro-2-(4-chlorophenoxy)-benzenamin CAS 121-27-7
5-Chloro-2-(4-chlorophenoxy)benzenamine (CAS 121-27-7) is a halogenated aromatic amine compound serving as a versatile building block in organic synthesis, particularly for dyes and pharmaceutical intermediates due to its reactive amino group and ether linkage.
5-chloro-2-(4-chlorophenoxy)-benzenamin CAS 121-27-7
- CAS: 121-27-7
- Molecular Formula: C12H9Cl2NO
- Molecular Weight: 254.11
- EINECS: 204-460-5
- HS Code: 2922290090
- Synonyms: 2-Amino-4,4'-Dichlorodiphenyl Ether; 5-chloro-2-(4-chlorophenoxy)-benzenamin;5-chloro-2-(4-chlorophenoxy)-Benzenamine;AURORA KA-6780;Benzenamine,5-chloro-2-(4-chlorophenoxy)-;C.I.Azoic Diazo Component 33;Diazo Fast Red FR;Fast Red FR Base;Fast Red Salt FRN.
What is 5-chloro-2-(4-chlorophenoxy)-benzenamin CAS 121-27-7?
5-chloro-2-(4-chlorophenoxy)benzenamine CAS 121-27-7 is a chlorinated aromatic amine with an ether-linked structure (C₁₂H₉Cl₂NO, 254.11 g/mol), combining reactivity (amino/chlorine groups) for nucleophilic reactions. It enables vibrant textile dyes, potential therapeutics, and proteomics research. Synthesized via nitro-reduction or etherification, it bridges lab chemistry to industrial and biomedical innovations.
Specifications
| Property | Value |
|---|---|
| Melting point | 61.0 to 65.0 °C |
| Boiling point | 234°C/27mmHg(lit.) |
| Density | 1.386 g/mL at 25 °C(lit.) |
| Color | White to Yellow to Orange |
| Form | powder to crystal |
| pka | 2.99±0.10(Predicted) |
| Storage Temp. | Keep in a dark place, Inert atmosphere, Room temperature |
Features
- Physical Properties: Solid at room temperature with a melting point of ~67°C; soluble in organic solvents like ethanol or acetone, but limited water solubility due to its non-polar aromatic structure.
- Chemical Reactivity: The primary amino group enables nucleophilic reactions, such as diazotization or coupling, while the ether linkage provides stability; the chlorine substituents enhance lipophilicity and metabolic resistance in derived compounds.
- Safety Profile: Harmful if swallowed, inhaled, or absorbed through skin; causes eye and skin irritation; handle with protective equipment in well-ventilated areas, as it may release toxic fumes when heated.
Applications
- Dye Synthesis: Acts as an intermediate for azo and acid dyes, including high-fastness disperse dyes, due to its ability to form colored complexes in textile coloration.
- Pharmaceutical Intermediates: Used in the preparation of bioactive molecules, such as potential antifungal or anti-inflammatory agents, leveraging its halogenated structure for drug-like properties.
- Research and Biochemical Tools: Employed in proteomics and organic synthesis for creating enzyme inhibitors or fluorescent probes, often in academic and industrial R&D.
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