2-Methyl-2-hydroxypropionamide CAS 13027-88-8

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2-Methyl-2-hydroxypropionamide CAS 13027-88-8

CAS: 13027-88-8
Molecular Formula: C4H9NO2
Molecular Weight: 103.12
EINECS: 235-890-1
HS Code: 2924.19.8000

Synonyms: 2-Hydroxyisobutylamide; 2-HYDROXYISOBUTYRAMIDE (2-METHYL-2-HYDROXYPROPIONAMIDE, METHYLLACTAMIDE); 2-Hydroxyisobutyric acid, amide; α-Hydroxyisobutyramide; Methyl-2-lactamide; 2-Methyl-2-hydroxypr; 2-Hydroxyisobutyric acid amid; 2-METHYL-2-HYDROXYPROPIONAMIDE

What is 2-Methyl-2-hydroxypropionamide CAS 13027-88-8?

2-Methyl-2-hydroxypropionamide CAS 13027-88-8, also widely known as 2-hydroxyisobutyramide or alpha-hydroxyisobutyramide, is an organic compound belonging to the aliphatic amide family. Featuring a compact branched carbon backbone substituted with both a primary amide group and a tertiary hydroxyl group, this compound functions as a highly specialized bifunctional building block. It is an essential structural intermediate in the synthesis of methacrylate polymers, advanced pharmaceuticals, and specialty fine chemicals.

Specifications

Property Value
Appearance White to off-white crystalline solid
Melting Point 93 °C
Boiling Point 260 °C
Density 1.109 ± 0.06 g/cm³ (Predicted)
pka 13.41 ± 0.29 (Predicted)
Storage Conditions Store sealed in a cool, dry place at room temperature. Keep container tightly closed in a well-ventilated storage area away from moisture, intense heat, and strong oxidizing agents or strong acids.

Features

  • Bifunctional Aliphatic Core: Concurrently contains a reactive tertiary alcohol and a primary amide moiety, presenting unique chemical pathways for dehydration, esterification, and cyclization.
  • High Industrial Purity: Formulated to superior technical and analytical standards to guarantee dependable conversion kinetics, uniform batch metrics, and minimized volatile side products.
  • Stable Crystalline Solid: Delivered as a robust, non-dusting crystalline powder that offers straightforward physical handling, safe storage behavior, and accurate commercial plant batching.
  • Predictable Monomer Precursor: Readily undergoes controlled dehydration to yield highly valued acrylic or methacrylic monomers under appropriate catalytic conditions.

Applications

  • Chemical Synthesis & Polymers: Extensively utilized as an industrial process intermediate for producing methyl methacrylate (MMA), specialized polymethacrylate resins, and clear performance plastics.
  • Pharmaceutical Research: Applied as a highly reliable structural block or intermediate in medicinal chemistry pipelines for structural decoration, targeted molecule design, and active ingredient development.
  • Specialty Chemicals: Incorporated directly as a specialized raw material in custom formulations where a low-molecular-weight hydroxy-functionalized amide is required to crosslink or modify downstream resin networks.
  • Laboratory R&D: Deployed as a key research reagent, analytical standard, or process probe in academic and industrial chemical laboratories evaluating alpha-hydroxy acid derivatives.

Packaging

Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.

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