What is 2-Methyl-2-hydroxypropionamide CAS 13027-88-8?
2-Methyl-2-hydroxypropionamide CAS 13027-88-8, also widely known as 2-hydroxyisobutyramide or alpha-hydroxyisobutyramide, is an organic compound belonging to the aliphatic amide family. Featuring a compact branched carbon backbone substituted with both a primary amide group and a tertiary hydroxyl group, this compound functions as a highly specialized bifunctional building block. It is an essential structural intermediate in the synthesis of methacrylate polymers, advanced pharmaceuticals, and specialty fine chemicals.
Specifications
| Property |
Value |
| Appearance |
White to off-white crystalline solid |
| Melting Point |
93 °C |
| Boiling Point |
260 °C |
| Density |
1.109 ± 0.06 g/cm³ (Predicted) |
| pka |
13.41 ± 0.29 (Predicted) |
| Storage Conditions |
Store sealed in a cool, dry place at room temperature. Keep container tightly closed in a well-ventilated storage area away from moisture, intense heat, and strong oxidizing agents or strong acids. |
Features
- Bifunctional Aliphatic Core: Concurrently contains a reactive tertiary alcohol and a primary amide moiety, presenting unique chemical pathways for dehydration, esterification, and cyclization.
- High Industrial Purity: Formulated to superior technical and analytical standards to guarantee dependable conversion kinetics, uniform batch metrics, and minimized volatile side products.
- Stable Crystalline Solid: Delivered as a robust, non-dusting crystalline powder that offers straightforward physical handling, safe storage behavior, and accurate commercial plant batching.
- Predictable Monomer Precursor: Readily undergoes controlled dehydration to yield highly valued acrylic or methacrylic monomers under appropriate catalytic conditions.
Applications
- Chemical Synthesis & Polymers: Extensively utilized as an industrial process intermediate for producing methyl methacrylate (MMA), specialized polymethacrylate resins, and clear performance plastics.
- Pharmaceutical Research: Applied as a highly reliable structural block or intermediate in medicinal chemistry pipelines for structural decoration, targeted molecule design, and active ingredient development.
- Specialty Chemicals: Incorporated directly as a specialized raw material in custom formulations where a low-molecular-weight hydroxy-functionalized amide is required to crosslink or modify downstream resin networks.
- Laboratory R&D: Deployed as a key research reagent, analytical standard, or process probe in academic and industrial chemical laboratories evaluating alpha-hydroxy acid derivatives.
Packaging
Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.