3-Aminobenzoylmethylamide CAS 25900-61-2

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3-Aminobenzoylmethylamide CAS 25900-61-2

CAS: 25900-61-2
Molecular Formula: C8H10N2O
Molecular Weight: 150.18
EINECS: 233-675-7
HS Code: 2924.29.7790

Synonyms: 3-AMINO-N-METHYLBENZAMIDE; 3-AMINOBENZOYLMETHYLAMIDE; BUTTPARK25\02-27; Benzamide, 3-amino-N-methyl- (9CI); 3-AMINOBENZOYLMETHYLAMIDE 98+%; N-Methyl-3-aminobenzamide; 3-Amino-N-methylbenzamide; 3-(Methylcarbamyl)aniline

What is 3-Aminobenzoylmethylamide CAS 25900-61-2?

3-Aminobenzoylmethylamide CAS 25900-61-2, also widely known as 3-amino-N-methylbenzamide or 3-(methylcarbamoyl)aniline, is an aromatic organic compound belonging to the benzamide derivative family. Featuring a benzene core functionalized with both a reactive meta-amino group and a stable secondary methylamide group, it serves as a highly specialized building block. It is primarily supplied at high purity for use as an intermediate in advanced organic synthesis, medicinal chemistry drug discovery platforms, and industrial chemical research.

Specifications

Property Value
Appearance White to light yellow to light red powder to crystalline
Melting Point 119 °C
Boiling Point 346.7 ± 25.0 °C (Predicted)
Density 1.137 ± 0.06 g/cm³ (Predicted)
pka 15.19 ± 0.46 (Predicted)
Storage Conditions Store in a dark place, sealed in a dry environment at room temperature. Keep container tightly closed in a cool, well-ventilated storage area away from moisture, heat, open flames, and strong oxidizing agents.

Features

  • Bifunctional Benzamide Core: Combines a nucleophilic meta-positioned primary amine with an N-methylamide tail, offering excellent structural properties for regioselective synthesis and molecular engineering.
  • High Synthetic Purity: Formulated to superior industrial specifications (≥98% by HPLC) to ensure highly predictable performance, minimal side reactions, and clean crystallization phases.
  • Stable Solid Configuration: Delivered as a robust, uniform crystalline powder or solid matrix, providing easier physical handling, long-term storage stability, and precise plant batching compared to liquid amines.
  • Favorable Scaffold Reactivity: The amino handle easily undergoes standard acylation, alkylation, diazotization, or transition-metal catalyzed cross-coupling without affecting the secondary amide framework.

Applications

  • Organic Synthesis: Extensively utilized as an organic building block and intermediate to prepare highly substituted benzamide derivatives, specialized nitrogen heterocycles, and custom coupling products.
  • Medicinal Chemistry: Heavily applied in drug discovery pipelines and academic research to build or modify pharmacologically relevant small-molecule scaffolds, enzyme inhibitors, and complex active pharmaceutical ingredients (APIs).
  • Laboratory Research: Deployed as a reliable analytical standard, chemical probe, or diagnostic reagent in laboratory R&D, process optimization trials, and custom validation methodologies.
  • Fine Chemical & Dye Production: Serves as an upstream structural material for constructing high-performance organic additives, photo-stabilizers, and targeted industrial functional molecules.

Packaging

Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.

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