What is 3-BroMo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid CAS 500011-86-9?
3-BroMo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid CAS 500011-86-9 is a halogenated pyrazole carboxylic acid derivative that serves as a versatile intermediate in organic synthesis, particularly for constructing complex heterocyclic structures in agrochemical and pharmaceutical research.
Specifications
| Property |
Value |
| Appearance |
White to Light Brown Solid |
| Melting Point |
197-200 °C |
| Boiling Point |
477.4±45.0 °C(Predicted) |
| Density |
1.92±0.1 g/cm3(Predicted) |
| pka |
2.39±0.36(Predicted) |
| Storage Conditions |
Store at 2–8 °C, keep in a cool, dry, and well-ventilated place |
Features
- Organic Intermediate: Acts as a synthetic building block in multi‑step organic reactions.
- Heterocyclic Core: Contains a substituted pyrazole and chloropyridine moiety ideal for elaboration into diverse chemical scaffolds.
- Halogen Functionalities: Bromine and chlorine substituents enable further functionalization via cross‑coupling or substitution reactions.
- Research Utility: Valued in medicinal chemistry and agrochemical discovery for structural diversity and reactivity.
Applications
- Agrochemical Synthesis: Used as a key intermediate in the production of crop protection agents such as insecticides (e.g., Chlorantraniliprole/Coragen) and related compounds.
- Pharmaceutical Discovery: Serves as a building block for synthesizing potential drug candidates and heterocyclic libraries.
- Medicinal Chemistry Research: Applied in academic and industrial research to explore structure‑activity relationships of bioactive heterocycles.
- Organic Synthesis: Used in synthetic chemistry for constructing complex organic molecules with multiple functional handles.
- Chemical R&D: Utilized in research and development settings for designing and optimizing new molecules with specific target activities.
Packaging
Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.
