Acetamidine hydrochloride CAS 124-42-5

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Acetamidine hydrochloride CAS 124-42-5

CAS: 124-42-5
Molecular Formula: C2H7ClN2
Molecular Weight: 94.54
EINECS: 204-700-9

Synonyms: ACETAMIDINIUM CHLORIDE; ACEDIAMINE HYDROCHLORIDE; Ethaneamidinehydrochloride; ethanimidamide,monohydrochloride; Ethylamidinehydrochloride; Acetalmidine hydrochioride; Acetamidine; ACECAMIDINE HYDROCHLORIDE

What is Acetamidine hydrochloride CAS 124-42-5?

Acetamidine hydrochloride CAS 124-42-5, also known as ethanimidamide hydrochloride, is an amidine-based compound typically obtained as a hydrochloride salt and extensively applied as a nitrogen-containing building block in organic synthesis, especially for the preparation of heterocycles, pharmaceuticals, and bioactive molecules.

Specification

Item Value
Appearance White to cream Crystalline Powder, Crystals and/or Chunks
Melting Point 165-170 °C(lit.)
Boiling Point 129.78°C (rough estimate)
Density 1.0596 (rough estimate)
pka pK1: 1.60(+1) (25°C)
Storage Temp Inert atmosphere, Room Temperature

Feature

  • Amidine Type: Belongs to the amidine class, serving as a nitrogen-rich synthetic intermediate.
  • Reactive Reagent: Acts as an effective ammonia-equivalent source in various substitution and coupling reactions.
  • Synthesis Versatility: Enables formation of diverse nitrogen-containing heterocycles and derivatives.
  • Pharma Relevance: Widely used in the development of pharmaceutical intermediates and bioactive compounds.
  • Stable Salt Form: Commonly handled as a hydrochloride salt, facilitating storage and industrial use.

Application

  • Vitamin Synthesis: Key raw material in the production of vitamin B1 (thiamine).
  • Antibiotic Intermediate: Used in synthesizing imidazole, pyrimidine, and triazine-based antimicrobial compounds.
  • Heterocycle Building: Applied in the preparation of nitrogen-containing heterocyclic compounds.
  • Organic Reagent: Functions as a reagent in nucleophilic substitution and catalytic amination reactions.
  • Pharma Intermediate: Serves as a precursor in active pharmaceutical ingredient (API) synthesis.

Packaging

Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.

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