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CAS: 147-24-0
Molecular Formula: C17H22ClNO
Molecular Weight: 291.82
EINECS: 205-687-2
HS Code: 29221990
Synonyms: 2-(diphenylmethoxy)-n,n-dimethyl-ethanaminhydrochloride; 2-(diphenylmethoxy)-n,n-dimethyl-ethylaminhydrochloride; Actifed; alpha-Hydroxydiphenylmethane-beta-dimethylaminoethyl ether hydrochloride; alpha-hydroxydiphenylmethane-beta-dimethylaminoethyletherhydrochloride; Ambenyl; Benadril hydrochloride; Benadryl hydrochloride
Diphenhydramine Hydrochloride CAS 147-24-0 is the hydrochloride salt form of diphenhydramine, a well-known first-generation ethanolamine antihistamine. It typically appears as a white or almost white crystalline powder, odorless with a bitter, numbing taste, and is exceptionally soluble in water and alcohol.
Widely recognized for its potent antihistaminic, anticholinergic (drying), and sedative properties, Diphenhydramine Hydrochloride competitively blocks histamine H1 receptors and muscarinic cholinergic receptors. It is extensively utilized in human and veterinary medicine for managing allergic conditions, motion sickness, parkinsonism symptoms, and as a sleep aid or antiemetic.
| Property | Value |
| Appearance | White or almost white crystalline powder |
| Melting Point | 168-172 °C |
| Boiling Point | 163-167 °C (Press: 3 Torr) |
| Density | 1.0489 (rough estimate) |
| pH | 4.0 to 5.5 (100 g/L, 25 °C) |
| Water Solubility | 1000 g/L (Very soluble in water, freely soluble in alcohol) |
| Storage Conditions | Store at 2 °C to 8 °C in a desiccated area, protected from light |
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Our R&D laboratory, staffed by experienced chemists and engineers, drives continuous innovation— developing high-performance chemical solutions tailored to diverse industries. From raw material analysis to final product inspection, we maintain full traceability and consistency.
Founded in 2020, Mikem Chemical Group Co., Ltd. is a trusted global partner in the chemical supply chain, offering a wide range of inorganic and organic compounds, cleaning agents, pigments, additives, and APIs. With over 300 employees and a 20,000 m² facility integrating production, R&D, testing, and storage, Mikem delivers reliable products and tailored solutions that create lasting value for customers worldwide.
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At Mikem, our advanced factory and laboratory form the foundation of our chemical production excellence. Equipped with modern manufacturing lines and precision testing instruments, we ensure every product meets strict international standards for quality, safety, and performance.
Our R&D laboratory, staffed by experienced chemists and engineers, drives continuous innovation— developing high-performance chemical solutions tailored to diverse industries. From raw material analysis to final product inspection, we maintain full traceability and consistency.
