What is Indometacin CAS 53-86-1?
Indometacin CAS 53-86-1 is an orally active non-steroidal anti-inflammatory research compound with potent inhibition of cyclooxygenase (COX) enzymes, making it valuable in studies of inflammation pathways, prostaglandin biosynthesis, and related pharmacological models. It is supplied as a white to off-white crystalline powder and is commonly used as a reference standard or intermediate in pharmaceutical and biochemical research.
Specification
| Item |
Value |
| Appearance |
White to off-white powder to light yellow/light orange powder |
| Melting Point |
158–162 °C |
| Boiling Point |
499.4±45.0 °C (predicted) |
| Density |
1.2135 g/cm³ (estimate) |
| Storage Conditions |
Store at room temperature (cool, dry place) |
Feature
- Potent Anti-Inflammatory Agent: Exhibits strong inhibitory effects on cyclooxygenase enzymes, making it a key compound for studying prostaglandin-mediated inflammation pathways in vitro and in preclinical models.
- Broad Research Applicability: Widely used as a research reference standard in pharmacology, biochemistry, and analytical method development.
- Crystalline Solid Form: Stable, well-defined solid suitable for formulation research and analytical calibration studies.
- Organic Solvent Solubility: Compatible with common organic solvents for solution preparation in laboratory protocols.
Application
- Pharmacological Research: Utilized in studies examining cyclooxygenase inhibition, prostaglandin biosynthesis mechanisms, and inflammatory response modulation.
- NSAID Mechanism Studies: Used as a model compound in research into non-steroidal anti-inflammatory drug (NSAID) activity and comparative efficacy profiling.
- Analytical Standard: Employed as a reference or calibration standard in HPLC, LC-MS, and other analytical methods in pharmaceutical quality control and research settings.
- Intermediate in Synthesis: Applied as an intermediate in medicinal chemistry and synthetic studies of related anti-inflammatory analogs.
Packaging
Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.