LDAO CAS 1643-20-5

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LDAO CAS 1643-20-5

CAS: 1643-20-5
Molecular Formula: C14H31NO
Molecular Weight: 229.4
EINECS: 216-700-6
HS Code: 2929.90.9090

Synonyms: oxydededimethyllaurylamine; refan; Dodecycldimethylamine oxide; DDAO, Lauryldimethylamine N-oxide, LDAO; LADO; n-Dodeycl-N,N-dimethylamine-N-oxide; N,N-dimethyldodecan-1-amine oxide; Barlox(R) 1260

What is LDAO CAS 1643-20-5?

LDAO CAS 1643-20-5, also known as Lauryldimethylamine oxide (or dodecyldimethylamine oxide / DDAO), is a zwitterionic amine oxide surfactant containing a hydrophobic twelve-carbon alkyl tail linked to a highly polar, hydrophilic amine oxide head group. Depending on the pH of the system, it exhibits non-ionic properties under neutral and alkaline conditions and cationic characteristics in acidic environments. Widely valued for its unique amphiphilic nature, LDAO is a premier detergent utilized extensively in membrane protein structural biology, as well as an excellent foam stabilizer and viscosity modifier in commercial personal care and cleaning formulations.

Specifications

Item Value
Appearance White to off-white crystalline solid
Melting Point 132-133 °C(lit.)
Boiling Point 371.32°C (rough estimate)
Density 0.996 g/mL at 20 °C
Fp 113°C
pka 4.79±0.40(Predicted)
Form A crystalline solid
pH 7.0-9.0 (25°C, 0.1M in H2O)
Storage Temp. -20°C

Features

  • Amphiphilic Surfactant Behavior: Forms highly uniform micelles at low critical micelle concentration (CMC) values, allowing it to efficiently partition and interact with both hydrophobic matrices and polar aqueous environments.
  • Mild, Non-Denaturing Detergent: Possesses a gentle token of action that easily solubilizes fragile membrane-bound proteins and assemblies without disrupting their secondary structures or native enzymatic activities.
  • Exceptional Foam & Viscosity Boosting: Acts as an outstanding foam builder and rheology modifier, creating rich, dense, and highly stable creamy lathers in surfactant matrices.
  • Broad Formulation Synergy: Blends seamlessly with anionic, non-ionic, and amphoteric surfactants, actively mitigating the skin irritation potential of harsher primary detergents like SLES while enhancing overall antistatic and conditioning performance.

Applications

  • Membrane Protein Research & Purification: Extensively utilized by structural biologists and biochemists to extract, solubilize, and stabilize hydrophobic membrane-bound targets, including ion channels, receptors, and respiratory complexes.
  • X-ray Crystallography & Protein Analysis: Heavily relied upon in membrane protein crystallization trials, nuclear magnetic resonance (NMR) spectroscopy, and high-molecular-weight protein detection workflows.
  • Cosmetics & Personal Care: Formulated into premium shampoos, liquid hand soaps, facial washes, and bubble baths as a dependable conditioning agent, stabilizer, detangler, and viscosity modifier.
  • Household & Industrial Cleaning: Incorporated into high-performance liquid dishwashing detergents and hard-surface cleaners where rapid grease emulsification, low residue tracking, and deep wetting are required.
  • Mixed-Surfactant Engineering: Applied as a secondary surfactant tool to customize texture profiles, reduce skin-stripping effects, and improve long-term thermal stability in multi-component commercial emulsions.

Packaging

Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.

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