Monensin Sodium Salt CAS 22373-78-0

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Monensin Sodium Salt CAS 22373-78-0

CAS: 22373-78-0
Molecular Formula: C36H61NaO11
Molecular Weight:710.87
EINECS: 244-941-7

Synonyms: Coban45; gamma,2,8-tetramethyl–furyl)-2-furyl)-9-hydroxy-beta-methoxy-alphmonosod; methyl-5-(tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2h-pyran-2-yl)-2; monensin,monosodiumsalt; Monensin,monosodiumsalt(9CI); Previouscas:22136-43-2; Sodiummonensin; 2-[5-Ethyltetrahydro-5-[tetrahydro-3-Methyl-5-[tetrahydro-6-hydroxy-6-(hydroxyMethyl)-3,5-diMethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-Methoxy-α,γ,2,8-tetraMethyl-

What is Monensin Sodium Salt CAS 22373-78-0?

Monensin Sodium Salt CAS 22373-78-0 is the sodium salt form of monensin, a naturally derived polyether antibiotic produced by Streptomyces species. It functions as a sodium-selective ionophore, forming lipid-soluble complexes with monovalent cations and facilitating their transport across cell membranes. This unique mechanism underlies its biological activity and supports its use in biochemical research, antimicrobial studies, and veterinary science.

Specification

Item Value
Appearance White to off-white solid
Melting Point 267–269 °C
Storage conditions Store at 2–8 °C, cool and dry place

Feature

  • Selective Sodium Ionophore: Exhibits strong selectivity for monovalent cations, particularly sodium ions, enabling controlled ion transport across lipid membranes in biological systems.
  • Polyether Antibiotic Structure: The multi-ring polyether framework provides high lipophilicity and membrane affinity, supporting its biological and antimicrobial activity.
  • Reliable Solid Stability: Supplied as a stable crystalline or powder solid suitable for controlled laboratory handling and long-term storage under recommended conditions.
  • Well-Established Biological Tool: Extensively used as a functional probe in studies of ion gradients, intracellular trafficking, and membrane-associated processes.

Application

  • Membrane Transport & Cell Biology Research: Used to study ion transport mechanisms, intracellular sodium balance, and membrane permeability in cellular models.
  • Antimicrobial Mechanism Studies: Applied as a model compound for investigating ionophore-based antibacterial activity, particularly against Gram-positive microorganisms.
  • Veterinary & Animal Health Research: Utilized as a reference compound and research intermediate in studies related to feed efficiency, coccidiosis control, and ruminant metabolism.
  • Metabolic & Signal Pathway Investigation: Employed in biochemical research exploring mitochondrial function, cellular metabolism, apoptosis, and ion-dependent signaling pathways.

Packaging

Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.

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