What is Probenecid CAS 57-66-9?
Probenecid CAS 57-66-9 is an organic compound originally developed as a uricosuric agent to increase the excretion of uric acid in the urine, making it relevant for studies of chronic gout, hyperuricemia, and renal tubular transport mechanisms. In research settings, it is employed as a reference standard or intermediate in pharmacological, enzymology, and transporter biology studies, particularly those involving urate transport inhibition and drug disposition.
Specification
| Item |
Value |
| Appearance |
White to off-white crystalline powder |
| Melting Point |
194–196 °C |
| Boiling Point |
~438.0 ±47.0 °C (predicted) |
| Density |
~1.2483 g/cm³ (estimated) |
| Storage Condition |
Room temperature, cool and dry place |
Feature
- Uricosuric Activity Model Compound– Probenecid is a classic uricosuric agent that inhibits the active reabsorption of urate in renal proximal tubules, making it useful in studies of urate transport mechanisms and renal physiology.
- Reference Standard for Transporter Research – Widely used as a comparative standard in biochemical studies investigating membrane transporters, including organic anion transport systems.
- Stable Crystalline Solid– Provided as a white to off-white crystalline powder with good solid-state stability under standard laboratory storage conditions.
- Solvent Compatibility – Slight solubility in organic solvents such as DMSO and methanol supports preparation of stock solutions for in vitro assays.
Application
- Renal & Uric Acid Research– Used in in vitro and biochemical studies examining urate transporters, renal tubular mechanisms, and uric acid excretion pathways.
- Pharmacological & Medicinal Chemistry– Applied as a reference standard or intermediate in studies of transporter inhibition, drug disposition, and interaction with organic anion pathways.
- Analytical & Enzymology Studies– Utilized in analytical method development and enzymology research focused on transport proteins and urate metabolism.
Packaging
Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.
