What is Reactive Blue 4 CAS 13324-20-4?
Reactive Blue 4 CAS 13324-20-4, also known as C.I. Reactive Blue 19, Procion Blue MX-R, or 1-amino-4-[3-(4,6-dichlorotriazin-2-ylamino)-4-sulfophenylamino]anthraquinone-2-sulfonic acid, is a water-soluble dye featuring a dichlorotriazine reactive group that enables nucleophilic substitution with hydroxyl groups on cotton under alkaline conditions, forming stable covalent bonds for high color fastness; it is commonly supplied as a 35% dye content powder and, while effective in dyeing, acts as an environmental pollutant treatable via microbial fuel cells or adsorption methods.
Specification
| Item |
Value |
| Boiling Point |
291°C (rough estimate) |
| Density |
1.5315 (rough estimate) |
| Refractive Index |
1.6000 (estimate) |
| pka |
-1.22±0.20(Predicted) |
| Color |
Blue to dark blue |
| Form |
saline suspension |
| Storage Temp. |
2-8°C |
Feature
- Physical Properties: Blue powder with a molecular weight of 637.43 g/mol, high water solubility due to sulfonate groups, and a topological polar surface area of 248 Ų with 5 hydrogen bond donors; typically provided at 35% dye content in commercial formulations.
- Chemical Reactivity: Contains a labile dichlorotriazine moiety for covalent attachment to substrates via nucleophilic aromatic substitution; stable under neutral conditions but hydrolyzes in water or reacts under alkaline pH (8-11) for dyeing; incompatible with strong acids or reducing agents.
- Synthesis: Prepared through condensation of an anthraquinone intermediate (like H-acid derivative) with cyanuric chloride, followed by coupling and sulfonation steps, often yielding technical-grade products with purity around 35-50%.
- Safety Profile: May cause skin, eye, or respiratory irritation upon contact or inhalation; not considered acutely toxic or harmful to aquatic life with low long-term environmental effects per SDS, but requires protective handling and wastewater treatment to prevent pollution; non-flammable and stable under normal storage.
Application
- Textile Dyeing: Primarily used for exhaust dyeing and printing on cotton, viscose, and other cellulosic fibers, offering brilliant turquoise-blue shades with excellent wash, light, and perspiration fastness.
- Chromatography and Purification: Employed as a ligand in affinity chromatography dye resins for protein purification and enzyme immobilization due to its specific binding to biomolecules.
- Analytical and Research Tools: Serves as a reference standard for method validation, quality control in drug development, and as a colorimetric chemosensor for detecting multiple analytes in aqueous media with distinct optical responses.
- Environmental and Wastewater Treatment Studies: Utilized as a model pollutant in research on dye decolorization techniques, including microbial fuel cells, adsorption, and photocatalytic degradation.
Packaging
Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.
