What is Cyanoacetic acid CAS 372-09-8?
Cyanoacetic acid CAS 372-09-8 is a nitrile-substituted carboxylic acid that serves as a valuable building block in organic synthesis. Due to the presence of both nitrile and carboxyl functional groups, it participates in numerous chemical reactions and is widely used to produce pharmaceuticals, agrochemicals, adhesives, and fine chemicals. Industrially, it is an important intermediate for synthesizing heterocyclic compounds, cyanoacetate derivatives, and cyanoacrylate materials used in adhesives and coatings.
Specifications
| Property |
Value |
| Appearance |
White to light beige Adhering Crystalline Solid |
| Melting Point |
65 °C |
| Boiling Point |
108 °C / 0.15 mm Hg (lit.) |
| Density |
1.3676 (rough estimate) |
| pka |
2.45 (at 25℃) |
| pH |
1.6 (50g/l, H2O, 20℃) |
| Storage Conditions |
Store below +30°C. |
Features
- Dual Functional: Contains both nitrile and carboxyl groups, enabling diverse chemical transformations.
- Reactive Intermediate: Frequently used as a key intermediate for synthesizing heterocyclic and specialty organic compounds.
- Industrial Versatility: Applicable across pharmaceutical, agrochemical, and dye manufacturing sectors.
- Synthetic Utility: Participates in reactions such as cyanoacetylation, condensation, and cyclization in organic synthesis.
Applications
- Pharmaceuticals: Used as an intermediate in the synthesis of pharmaceutical compounds and active pharmaceutical ingredient (API) intermediates (such as Caffeine and Valproic Acid).
- Agrochemicals: Serves as a raw material for manufacturing certain pesticides and crop-protection intermediates.
- Adhesives: Used in the production of cyanoacrylate adhesives and related fast-curing bonding materials.
- Dye Industry: Acts as a precursor in the synthesis of dyes, pigments, and colorant intermediates.
- Organic Synthesis: Widely used as a reagent for preparing heterocycles, coumarins, and other fine chemical derivatives.
Packaging
Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.