What is L(-)-lactate CAS 687-47-8?
Ethyl L(-)-lactate CAS 687-47-8 is the (2S)-enantiomer of ethyl lactate, a FEMA (2440) approved edible flavor and GRAS-certified green chemical, existing as a clear colorless to pale yellow liquid with fruit-like odor. As a naturally occurring chiral building block, it has excellent biodegradability and low toxicity (LD50 orally in Rabbit >2000 mg/kg), making it an ideal alternative to traditional organic solvents. It is stable under storage below 30°C, supplied in 98%、99% and 99.5% high purity grades, and widely applied in organic synthesis, food, pharmaceutical, coating and daily chemical industries due to its chiral activity and solvent properties.
| Item |
Value |
| Appearance |
Clear colorless to pale yellow liquid |
| Melting point |
−26 °C(lit.) |
| Boiling point |
154 °C(lit.) |
| Density |
1.034 g/mL at 20 °C(lit.) |
| Flash point |
54.6±6.4 °C |
| pKa |
13.21±0.20(Predicted) |
| pH |
4 (50g/l, H2O, 20℃) |
| Optical Rotation |
[α]20/D 10.5±1°, neat |
| Storage Condition |
Store below +30°C, cool and ventilated |
Feature
1. Chiral Building Block Property – As a natural (2S)-enantiomer, it has specific chiral activity, serving as a key intermediate for the synthesis of chiral drugs, ligands and fine chemicals.
2. Eco-friendly Green Solvent – Biodegradable, low-toxic and non-polluting, compliant with environmental protection requirements, and is an ideal substitute for volatile organic solvents (VOCs) in chemical industry.
3. Multi-field Compatibility – Acts as both solvent and functional raw material, compatible with food, pharmaceutical, coating and daily chemical systems, with diverse application scenarios.
4. Approved Edible Flavor Grade – Certified by FEMA, with natural fruit-like aroma, suitable for direct use as food additive and flavoring ingredient.
5. Stable Physical and Chemical Properties – Stable under normal storage (below 30°C), with definite physical constants and optical rotation data, ensuring reproducibility of synthesis and formulation results.
6. High Purity Grade Optional – Supplied in 98% industrial grade, 99% pharmaceutical grade and 99.5% high-purity research grade, meeting strict quality requirements of different fields.
7. Excellent Solvent Performance – Balanced polarity, soluble in water and common organic solvents, suitable for multi-component reactions, cycloaddition and photochemical synthesis.
Application
1. Organic Synthesis – Used as a green solvent in ligand-free coupling reactions, asymmetric induction, photochemical synthesis and multi-component reactions; serves as a chiral building block for the synthesis of Lofexidine and other pharmaceutical intermediates, and chiral ligands.
2. Food Industry – Applied as a food additive and flavoring agent with fruit-like aroma, used in flavoring of beverages, candies, baked food and dairy products; also serves as a solvent for food colorants and preservatives.
3. Pharmaceutical Preparation – Used as a solvent and co-solvent in pharmaceutical formulations for improving solubility and bioavailability of poorly soluble drugs; acts as an intermediate for the synthesis of pharmaceutical raw materials and chiral drug derivatives.
4. Coating and Ink Industry – Employed as an environmentally friendly solvent in water-based coatings, UV-curable coatings and printing inks, reducing VOC emissions and improving product environmental performance.
5. Daily Chemical Production – Used in the formulation of cosmetics, perfumes and personal care products, acting as a solvent for active ingredients and a mild fragrance enhancer; also applied in cleaning products as a biodegradable cleaning agent.
6. Cellulose Product Processing – Serves as a solvent for nitrocellulose, cellulose acetate and cellulose ethers, used in the production of coatings, films and adhesives.
7. Analytical Chemistry – Used as a chiral solvent or derivatization reagent in chromatographic analysis for the separation and detection of chiral compounds, providing a basis for drug quality control and chemical research.
Packaging
Mikem offers flexible packaging options, including 25 kg of fiber drums for liquid products and 15–25 kg PP/PE bags for powder products, all customizable to meet your specific needs.